Gluten

By Perry McLimore, MD., JD. Introduction Gluten is a protein found in grassy grains such as wheat, rye, and barley. It provides elasticity to dough, and gluten helps the bread rise and keep its shape. Gluten is also used in multiple foodstuffs, cosmetics, and dermatomal preparations. For tens of thousands…

CAR-T Cell Therapy

Isharpal Singh, MS Programming T Cells to kill Tumor Cells Surgery, chemotherapy, and radiation therapy have been considered as the cornerstones of cancer therapy for years. But with the advent of targeted therapies like Imatinib (Gleevec®) and Trastuzumab (Herceptin®) there has been a considerable shift in the standard treatments for…

Aging and Anti-aging - A Telomere Trick

By Dr. Vaishali Kulkarni Telomeres are specific DNA-protein structures found at both ends of each chromosomes. They prevents the chromosome ends from sticking together and protecting chromosomes from degradation(1). The telomere regions are made up of repetitive nucleotide sequences. In vertebrates, the telomere sequence is TTAGGG and this…

Degronimids to degrade Oncoproteins

By IsharPal Singh, MS The past 20 years have brought an unprecedented increase in the accumulation of knowledge about cancer cells. The study of genomics has yielded a tremendous amount of data regarding the signaling cascades involved in cancerous cells. Yet, the increase in no. of deaths from cancer remind…

Human Microbiome and Autoimmunity

By Suchitra Chari, MS The human microbiome comprises of all the microorganisms and their genes present in the human body. This totals to around a trillion in number found in site specific places like the skin, mouth, nasal cavities, gut and uterus. When we use the term “microbe” in the…

Gamekeeper’s Thumb

By Perry McLimore, MD., JD. Gamekeeper’s thumb was described in 1955 due to chronic laxity found in the joint in Scottish gamekeepers.1 The gamekeepers would break the necks of small game by placing the neck of the animal between the ground and their thumbs. Skier’s thumb is…

Tommy John Elbow Surgery

By Perry McLimore, MD., JD. ELBOW The elbow is a synovial joint, which means the joint has a synovial capsule and is bathed in synovial fluid for cartilage nourishment. The bones that make up the elbow joint are the humerus, which is the upper arm bone. Below or distal to…

Shingles / Herpes Zoster Virus

By Joanne P. Shelby-Klein BSN RN The shingles vaccine, sometimes referred to as the ‘shingles shot’ is often seen advertised in pharmacies and Doctors’ offices, leading patients to wonder if they should get the vaccine and what is it for. Shingles is the layman’s term for the Herpes…