Taking a BiTE® out of Cancer

By Isharpal Singh, M.S. The Next Gen approach in Immunotherapy The era of modern antibody therapy began with the Prize-winning report on the basic structure of the immunoglobulin molecule given by Rodney Porter. His findings revealed two identical antigen-binding fragments (Fab) that blocked antigen precipitation by the…

Heart Diseases in Children

By Bhavana Sachdev, MS Heart is a muscular organ that pumps blood to all parts of our body. It consists of a network of blood vessels, such as arteries, veins, and capillaries which carry blood to and from all areas of the body. Any abnormality in the structure and function…

When Chronic Kidney Disease becomes End State, What Is Next?

By Joanne P. Shelby-Klein BSN RN Chronic Kidney Disease may continue to progress to the point where the kidneys are unable to filter enough of the waste products and excess fluid causing a build-up of fluid and toxins in the body. When this happens a person is said…

The Relation Between Gum Disease and Arthritis

Perry McLimore, MD., JD. Periodontitis and Arthritis Both arthritis and diseases of the oral cavity or mouth are common and severe health problems. Recently, researchers have found evidence of an association between periodontitis (gum disease) and arthritis (both osteoarthritis and rheumatoid arthritis (RA)). Bacteria that cause periodontitis have now been…

Diabetes: Type 1 and Type 2

 Neerja L. Bisht, MD Summary Diabetes or diabetes mellitus (Type I or Type II) is a long-term condition leading to increased blood sugar levels, also called hyperglycemia. The need to control these levels is very important as uncontrolled increase in blood sugar levels can lead to serious damage to…

Gene Therapy to Supercharge the Immune System

[icon name="user" class="" unprefixed_class=""]Isharpal Singh, MS A game-changing approach in Immune system research Benjamin franklin once said that only two things are certain in this world death and taxes. As our lives become longer on an average and our ability to treat a whole range of illnesses…

Chemo Brain, Is It Real or Is It Myth?

By Joanne P. Shelby-Klein BSN RN Fuzzy-headed, forgetful, mental fogginess, cancer patients who have received chemotherapy have talked and joked about this weird feeling for many years. Cancer Related Cognitive Dysfunction (CRCD) is the official name given to this collection of symptoms that is more commonly known as…

Measles: To Vaccinate or not to Vaccinate

[icon name="user" class="" unprefixed_class=""]  Perry McLimore, MD., JD. Introduction In the news recently is the account of a measles outbreak that apparently started in Disneyland, located in California. Currently, there are almost 100 confirmed cases of measles in California, Arizona, Utah, Washington State, Oregon, Colorado, Nebraska, and Mexico. It…